DB code: T00074
RLCP classification | 1.13.30000.10 : Hydrolysis | |
---|---|---|
CATH domain | 4.10.140.10 : Epsilon-Thrombin; Chain L | |
2.40.10.10 : Thrombin, subunit H | Catalytic domain | |
2.40.10.10 : Thrombin, subunit H | Catalytic domain | |
E.C. | 3.4.21.5 | |
CSA | ||
M-CSA | ||
MACiE |
CATH domain | Related DB codes (homologues) |
---|---|
2.40.10.10 : Thrombin, subunit H | M00139 D00214 M00167 D00426 M00133 D00428 D00429 D00430 D00431 D00432 D00433 D00434 D00435 M00227 M00209 D00194 D00197 D00211 D00212 D00216 M00212 D00224 D00497 M00217 M00216 D00528 D00848 D00850 D00851 D00852 D00855 M00152 M00155 M00157 M00181 M00315 M00316 M00317 M00348 M00349 T00410 T00411 |
Uniprot Enzyme Name | UniprotKB | Protein name | Synonyms | Contains | RefSeq | MEROPS | Pfam |
---|---|---|---|---|---|---|
P00734 |
Prothrombin
|
EC
3.4.21.5
Coagulation factor II |
Activation peptide fragment 1
Activation peptide fragment 2 Thrombin light chain Thrombin heavy chain |
NP_000497.1
(Protein)
NM_000506.3 (DNA/RNA sequence) |
S01.217
(Serine)
|
PF00594
(Gla)
PF00051 (Kringle) PF09396 (Thrombin_light) PF00089 (Trypsin) [Graphical View] |
P00735 |
Prothrombin
|
EC
3.4.21.5
Coagulation factor II |
Activation peptide fragment 1
Activation peptide fragment 2 Thrombin light chain Thrombin heavy chain |
NP_776302.1
(Protein)
NM_173877.1 (DNA/RNA sequence) |
S01.217
(Serine)
|
PF00594
(Gla)
PF00051 (Kringle) PF09396 (Thrombin_light) PF00089 (Trypsin) [Graphical View] |
KEGG enzyme name |
---|
thrombin
fibrinogenase thrombase thrombofort topical thrombin-C tropostasin activated blood-coagulation factor II blood-coagulation factor IIa factor IIa E thrombin beta-thrombin gamma-thrombin |
UniprotKB: Accession Number | Entry name | Activity | Subunit | Subcellular location | Cofactor |
---|---|---|---|---|---|
P00734 | THRB_HUMAN | Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B. | Secreted, extracellular space. | ||
P00735 | THRB_BOVIN | Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B. | Secreted, extracellular space. |
KEGG Pathways | Map code | Pathways | E.C. |
---|
Compound table | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Substrates | Products | Intermediates | ||||||||||
KEGG-id | C00012 | C00393 | C00001 | C00290 | C00952 | C02404 | ||||||
E.C. | ||||||||||||
Compound | Peptide | Fibrinogen | H2O | Fibrin | Fibrinopeptide A | Fibrinopeptide B | ||||||
Type | peptide/protein | peptide/protein | H2O | amine group,peptide/protein | peptide/protein | peptide/protein | ||||||
ChEBI |
15377 15377 |
5054 5054 |
||||||||||
PubChem |
22247451 962 22247451 962 |
439199 439199 |
||||||||||
1a2cL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1a3bL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1a3eL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1a46L | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1a4wL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1a5gL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1a61L | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1abiL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1abjL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ad8L | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ae8L | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1afeL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ahtL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ai8L | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1aixL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1avgL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1awfL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1awhA | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1awhB | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ay6L | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1b5gL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1b7xA | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ba8A | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bb0A | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bbrJ | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bbrL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bbrM | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bcuL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bhxA | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bmmL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bmnL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bthL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bthJ | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c1uL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c1vL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c1wL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c4u1 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c4v1 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c4y1 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c5lL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c5nL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c5oL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ca8A | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1d3dA | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1d3pA | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1d3qA | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1d3tA | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1d4pA | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1de7L | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1de7K | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ditL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1dwcL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1dwdL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1dweL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1dx5A | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1dx5B | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1dx5C | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1dx5D | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1etrL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1etsL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ettL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1fpcL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1fphL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1h8dL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1h8iL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hahL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1haiL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1haoL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hapL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hbtL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hdtL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hgtL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hltL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hltJ | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hrtL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hutL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hxeL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hxfL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ihsL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ihtL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1lhcL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1lhdL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1lheL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1lhfL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1lhgL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1mkwL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1mkxL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1nrpL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1nrrL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1nrsL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ppbL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1qbvL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1qhrA | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1qj1A | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1qj6A | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1qj7A | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1tbrJ | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1tbrL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1tbzL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1thpA | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1thrL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1thsL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1tmbL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1tmuL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1tomL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ucyJ | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ucyL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ucyM | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1umaL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1uvsL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1uvtL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1uvuL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ycpJ | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ycpL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
2hatL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
2hgtL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
2thfA | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
3hatL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
4htcL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
4thnL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
5gdsL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
7kmeL | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
8kme1 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1a2cH01 | Unbound | Unbound | Unbound | Analogue:ENO-2AC-RPH-OAR(chain R) | Unbound | Unbound | ||||||
1a3bH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:T29 | ||||||
1a3eH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:T16 | ||||||
1a46H01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:BIC-LYS-OHO(chain R) | ||||||
1a4wH01 | Analogue:ANS-ARG-2EP-KTH(chain R) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1a5gH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:BIC-ARG-EOA(chain R) | ||||||
1a61H01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:BIC-ARG-LOM(chain R) | ||||||
1abiH01 | Analogue:HMR_3-GLY_4(chain I) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1abjH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:PHE-PRO-ARG-CH2(chain I) | ||||||
1ad8H01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:MDL | ||||||
1ae8H01 | Analogue:AZL | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1afeH01 | Analogue:ALZ | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ahtH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:APA | ||||||
1ai8H01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:T42 | ||||||
1aixH01 | Analogue:T19 | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1avgH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1awfH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:GR4 | ||||||
1awhB01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:GR3 | ||||||
1awhD01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:GR3 | ||||||
1ay6H01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:HMF-PRO-ARG-HHO(chain I) | ||||||
1b5gH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:BCC-ARG-THZ(chain I) | ||||||
1b7xB01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-bound:PHE-PRO-ARG(chain C) | ||||||
1ba8B01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-bound:PMS-NVA-GLY-ARG(chain D) | ||||||
1bb0B01 | Analogue:PMS-NVA-GLY-3GA(chain D) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bbrE | Unbound | Unbound | Unbound | Bound:ARG_318(chain F) | Unbound | Unbound | ||||||
1bbrK01 | Unbound | Unbound | Unbound | Bound:ARG_318(chain G) | Unbound | Unbound | ||||||
1bbrN01 | Unbound | Unbound | Unbound | Bound:ARG_318(chain I) | Unbound | Unbound | ||||||
1bcuH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bhxF | Analogue:R56 | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bmmH01 | Analogue:BM2 | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bmnH01 | Analogue:BM9 | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bthH01 | Analogue:LYS_15-ALA_16(chain P) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bthK01 | Analogue:LYS_15-ALA_16(chain Q) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c1uH01 | Analogue:BAI | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c1vH01 | Analogue:BAB | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c1wH01 | Analogue:BAH | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c4u201 | Analogue:IH1 | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c4v201 | Analogue:IH2 | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c4y201 | Analogue:IH3 | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c5lH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c5nH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c5oH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ca8B01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:PMS-NVA-GLY-3GA(chain D) | ||||||
1d3dB01 | Analogue:BZT | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1d3pB01 | Analogue:BT3 | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1d3qB01 | Analogue:BT2 | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1d3tB01 | Analogue:BT1 | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1d4pB01 | Analogue:BPP | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1d6wA01 | Analogue:AIM-HMM-SML | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1d9iA01 | Analogue:CHN-HMM-SML | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1de7H01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-bound:PRO_36-ARG_37(chain A) | ||||||
1de7K01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-bound:THR-VAL-GLU-LEU-GLN-GLY-VAL-VAL-PRO-ARG(chain B) | ||||||
1ditH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:ARG_4-FMT_5(chain P) | ||||||
1dojA01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:CH3-DPN-PRO-AR2(chain I) | ||||||
1dwcH01 | Unbound | Unbound | Unbound | Analogue:MIT | Unbound | Unbound | ||||||
1dwdH01 | Analogue:MID | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1dweH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:PHE-PRO-ARG-CH2(chain P) | ||||||
1dx5M01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:GLU-GLY-ARM(chain E) | ||||||
1dx5N01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:GLU-GLY-ARM(chain F) | ||||||
1dx5O01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:GLU-GLY-ARM(chain G) | ||||||
1dx5P01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:GLU-GLY-ARM(chain H) | ||||||
1eojA01 | Analogue:CPI_3-TIH_4(chain B) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1eolA01 | Analogue:CPI_3-NLE_4(chain B) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1etrH01 | Unbound | Unbound | Unbound | Analogue:MQI-ARG-MCP(chain M) | Unbound | Unbound | ||||||
1etsH01 | Analogue:NAS-GLY-APH-PIP(chain N) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ettH01 | Analogue:TOS-APH-PIP(chain T) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1fpcH01 | Analogue:ANS-ARG-EPI(chain R) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1fphH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:ARG_16-CH2_17(chain F) | ||||||
1h8dH01 | Unbound | Unbound | Unbound | Analogue:PHW | Unbound | Unbound | ||||||
1h8iH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:PHW | ||||||
1hagE01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hahH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1haiH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:PHE-PRO-ARG-CH2(chain I) | ||||||
1haoH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:PHE-PRO-ARG-CH2(chain P) | ||||||
1hapH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:PHE-PRO-ARG-CH2(chain P) | ||||||
1hbtH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:ARG_3-PAA_3(chain I) | ||||||
1hdtH01 | Analogue:ALG-PHE-ALO-PHE-CH3(chain I) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hgtH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hltH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:PHE-PRO-ARG-CH2(chain I) | ||||||
1hltK01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:PHE-PRO-ARG-CH2(chain M) | ||||||
1hrtH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hutH01 | Unbound | Unbound | Unbound | Analogue:PHE-PRO-ARG-CH2(chain I) | Unbound | Unbound | ||||||
1hxeH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hxfH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ihsH01 | Analogue:ARG_3-CBG_3(chain I) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ihtH01 | Analogue:ARG_3-PTL_3(chain I) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1lhcH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:DP7 | ||||||
1lhdH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:DI2 | ||||||
1lheH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:DI3 | ||||||
1lhfH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:DI4 | ||||||
1lhgH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:DI5 | ||||||
1mkwH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1mkwK01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1mkxH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1mkxK01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1nrpH01 | Analogue:LEU-ASP-PRO-HMR-SER | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1nrrH01 | Unbound | Unbound | Unbound | Analogue:PHE-PRO-ARG-CH2(chain P) | Unbound | Unbound | ||||||
1nrsH01 | Unbound | Unbound | Unbound | Bound:LEU-ASP-PRO-ARG(chain R) | Unbound | Unbound | ||||||
1ppbH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:PHE-PRO-ARG-CH2(chain I) | ||||||
1qbvH01 | Analogue:PPX | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1qhrB01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:157 | ||||||
1qj1B01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:166 | ||||||
1qj6B01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:167 | ||||||
1qj7B01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:GR1 | ||||||
1tbrH01 | Analogue:HIS_10-ALA_11(chain R) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1tbrK01 | Analogue:HIS_10-ALA_11(chain S) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1tbzH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:DPN-PRO-ARG-THZ(chain R) | ||||||
1thpB01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:PHE-PRO-ARG-CH2(chain C) | ||||||
1thrH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1thsH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1tmbH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:FOR-ALA-PRO-ARG-FOR-PHE-AHT(chain T) | ||||||
1tmtH01 | Unbound | Unbound | Unbound | Bound:PHE-PRO-ARG(chain I) | Unbound | Unbound | ||||||
1tmuH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:PHE-PRO-ARG-CH2(chain I) | ||||||
1tomH01 | Analogue:MIN | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ucyE | Analogue:OPR_16(chain F) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ucyK01 | Analogue:OPR_16(chain G) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ucyN01 | Analogue:OPR_16(chain I) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1umaH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:IN2 | ||||||
1uvsH01 | Analogue:I11 | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1uvtH01 | Analogue:I48 | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1uvuH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ycpH01 | Bound:GLY-VAL-ARG-GLY-PRO(chain F) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ycpM | Bound:GLY-VAL-ARG-GLY-PRO(chain N) | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
2hatH01 | Unbound | Unbound | Unbound | Analogue:MBN-ABN-RNG-GLY-VAL-ARG-CH3(chain T) | Unbound | Unbound | ||||||
2hgtH01 | Unbound | Unbound | Unbound | Bound:PHE-PRO-ARG(chain I) | Unbound | Unbound | ||||||
2thfB01 | Unbound | Unbound | Unbound | Unbound | Unbound | Intermediate-analogue:PHE-PRO-ARG-CH2(chain C) | ||||||
3hatH01 | Unbound | Unbound | Unbound | Bound:RNG-GLY-VAL-ARG(chain T) | Unbound | Unbound | ||||||
4htcH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
4thnH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
5gdsH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
7kmeH01 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
8kme201 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1a2cH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1a3bH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1a3eH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1a46H02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1a4wH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1a5gH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1a61H02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1abiH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1abjH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ad8H02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ae8H02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1afeH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ahtH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ai8H02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1aixH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1avgH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1awfH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1awhB02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1awhD02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ay6H02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1b5gH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1b7xB02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ba8B02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bb0B02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bbrH | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bbrK02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bbrN02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bcuH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bhxB | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bmmH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bmnH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bthH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1bthK02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c1uH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c1vH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c1wH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c4u202 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c4v202 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c4y202 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c5lH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c5nH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1c5oH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ca8B02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1d3dB02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1d3pB02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1d3qB02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1d3tB02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1d4pB02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1d6wA02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1d9iA02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1de7H02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1de7K02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ditH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1dojA02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1dwcH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1dwdH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1dweH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1dx5M02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1dx5N02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1dx5O02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1dx5P02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1eojA02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1eolA02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1etrH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1etsH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ettH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1fpcH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1fphH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1h8dH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1h8iH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hagE02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hahH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1haiH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1haoH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hapH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hbtH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hdtH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hgtH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hltH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hltK02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hrtH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hutH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hxeH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1hxfH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ihsH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ihtH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1lhcH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1lhdH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1lheH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1lhfH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1lhgH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1mkwH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1mkwK02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1mkxH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1mkxK02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1nrpH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1nrrH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1nrsH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ppbH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1qbvH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1qhrB02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1qj1B02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1qj6B02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1qj7B02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1tbrH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1tbrK02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1tbzH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1thpB02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1thrH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1thsH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1tmbH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1tmtH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1tmuH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1tomH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ucyH | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ucyK02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ucyN02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1umaH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1uvsH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1uvtH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1uvuH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ycpH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
1ycpK | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
2hatH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
2hgtH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
2thfB02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
3hatH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
4htcH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
4thnH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
5gdsH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
7kmeH02 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound | ||||||
8kme202 | Unbound | Unbound | Unbound | Unbound | Unbound | Unbound |
Reference for Active-site residues | ||
---|---|---|
resource | references | E.C. |