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References
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[1]
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Resource
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Comments
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Medline ID
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PubMed ID
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7814421
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Journal
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J Biol Chem
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Year
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1995
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Volume
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270
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Pages
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66-72
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Authors
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Kazama Y, Hamamoto T, Foster DC, Kisiel W
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Title
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Hepsin, a putative membrane-associated serine protease, activates human factor VII and initiates a pathway of blood coagulation on the cell surface leading to thrombin formation.
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Related PDB
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Related UniProtKB
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[2]
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Resource
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Comments
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Medline ID
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PubMed ID
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9003440
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Journal
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Biochim Biophys Acta
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Year
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1997
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Volume
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1337
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Pages
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85-95
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Authors
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Zhukov A, Hellman U, Ingelman-Sundberg M
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Title
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Purification and characterization of hepsin from rat liver microsomes.
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Related PDB
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Related UniProtKB
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[3]
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Resource
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Comments
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Medline ID
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PubMed ID
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9395459
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Journal
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J Biol Chem
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Year
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1997
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Volume
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272
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Pages
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31315-20
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Authors
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Vu TK, Liu RW, Haaksma CJ, Tomasek JJ, Howard EW
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Title
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Identification and cloning of the membrane-associated serine protease, hepsin, from mouse preimplantation embryos.
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Related PDB
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Related UniProtKB
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[4]
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Resource
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Comments
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Medline ID
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PubMed ID
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12475199
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Journal
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Chem Rev
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Year
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2002
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Volume
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102
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Pages
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4501-24
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Authors
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Hedstrom L
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Title
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Serine protease mechanism and specificity.
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Related PDB
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Related UniProtKB
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[5]
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Resource
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Comments
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Medline ID
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PubMed ID
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12962630
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Journal
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Structure
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Year
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2003
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Volume
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11
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Pages
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1123-31
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Authors
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Somoza JR, Ho JD, Luong C, Ghate M, Sprengeler PA, Mortara K, Shrader WD, Sperandio D, Chan H, McGrath ME, Katz BA
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Title
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The structure of the extracellular region of human hepsin reveals a serine protease domain and a novel scavenger receptor cysteine-rich (SRCR) domain.
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Related PDB
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1p57
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Related UniProtKB
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P05981
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[6]
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Resource
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Comments
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Medline ID
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PubMed ID
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15522303
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Journal
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J Mol Biol
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Year
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2004
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Volume
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344
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Pages
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527-47
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Authors
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Katz BA, Luong C, Ho JD, Somoza JR, Gjerstad E, Tang J, Williams SR, Verner E, Mackman RL, Young WB, Sprengeler PA, Chan H, Mortara K, Janc JW, McGrath ME
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Title
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Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA).
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Related PDB
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1o5e
1o5f
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Related UniProtKB
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P05981
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[7]
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Resource
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Comments
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Medline ID
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PubMed ID
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15839837
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Journal
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Biochem J
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Year
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2005
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Volume
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390
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Pages
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125-36
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Authors
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Herter S, Piper DE, Aaron W, Gabriele T, Cutler G, Cao P, Bhatt AS, Choe Y, Craik CS, Walker N, Meininger D, Hoey T, Austin RJ
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Title
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Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers.
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Related PDB
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1z8g
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Related UniProtKB
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P05981
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[8]
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Resource
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Comments
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Medline ID
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PubMed ID
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15792801
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Journal
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FEBS Lett
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Year
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2005
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Volume
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579
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Pages
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1945-50
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Authors
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Kirchhofer D, Peek M, Lipari MT, Billeci K, Fan B, Moran P
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Title
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Hepsin activates pro-hepatocyte growth factor and is inhibited by hepatocyte growth factor activator inhibitor-1B (HAI-1B) and HAI-2.
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Related PDB
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Related UniProtKB
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[9]
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Resource
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Comments
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Medline ID
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PubMed ID
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16651711
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Journal
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Biol Pharm Bull
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Year
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2006
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Volume
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29
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Pages
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868-74
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Authors
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Kunii D, Shimoji M, Nakama S, Ikebe M, Hachiman T, Sato I, Tamaki A, Yamazaki K, Aniya Y
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Title
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Purification of liver serine protease which activates microsomal glutathione S-transferase: possible involvement of hepsin.
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Related PDB
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Related UniProtKB
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[10]
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Resource
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Comments
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Medline ID
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PubMed ID
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16908524
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Journal
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J Biol Chem
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Year
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2006
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Volume
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281
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|
Pages
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30439-46
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Authors
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Moran P, Li W, Fan B, Vij R, Eigenbrot C, Kirchhofer D
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Title
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Pro-urokinase-type plasminogen activator is a substrate for hepsin.
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Related PDB
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Related UniProtKB
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[11]
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Resource
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Comments
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Medline ID
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PubMed ID
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18784072
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Journal
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J Biol Chem
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Year
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2008
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Volume
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283
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Pages
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30576-84
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Authors
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Tripathi M, Nandana S, Yamashita H, Ganesan R, Kirchhofer D, Quaranta V
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Title
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Laminin-332 is a substrate for hepsin, a protease associated with prostate cancer progression.
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Related PDB
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Related UniProtKB
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[12]
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Resource
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Comments
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Medline ID
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PubMed ID
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20507279
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Journal
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Biochem J
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Year
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2010
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Volume
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428
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Pages
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325-46
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Authors
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Antalis TM, Buzza MS, Hodge KM, Hooper JD, Netzel-Arnett S
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Title
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The cutting edge: membrane-anchored serine protease activities in the pericellular microenvironment.
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Related PDB
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Related UniProtKB
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[13]
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Resource
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Comments
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Medline ID
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PubMed ID
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20410586
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Journal
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Biol Pharm Bull
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Year
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2010
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Volume
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33
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Pages
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561-7
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Authors
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Nakama S, Oshiro N, Aniya Y
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Title
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Activation of rat liver microsomal glutathione transferase by hepsin.
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Related PDB
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Related UniProtKB
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[14]
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Resource
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Comments
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Medline ID
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PubMed ID
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19911255
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Journal
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Mol Cell Biochem
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|
Year
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2010
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Volume
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337
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Pages
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259-66
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Authors
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Chen M, Chen LM, Lin CY, Chai KX
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Title
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Hepsin activates prostasin and cleaves the extracellular domain of the epidermal growth factor receptor.
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Related PDB
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Related UniProtKB
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[15]
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Resource
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Comments
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Medline ID
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PubMed ID
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22132769
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Journal
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Biochem J
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Year
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2012
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Volume
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442
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Pages
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483-94
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Authors
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Koschubs T, Dengl S, Durr H, Kaluza K, Georges G, Hartl C, Jennewein S, Lanzendorfer M, Auer J, Stern A, Huang KS, Packman K, Gubler U, Kostrewa D, Ries S, Hansen S, Kohnert U, Cramer P, Mundigl O
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Title
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Allosteric antibody inhibition of human hepsin protease.
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Related PDB
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3t2n
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Related UniProtKB
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