|
References
|
|
[1]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
3202970
|
|
Journal
|
Biol Chem Hoppe Seyler
|
|
Year
|
1988
|
|
Volume
|
369 Suppl
|
|
Pages
|
323-7
|
|
Authors
|
Bonelli G, Kay J, Tessitore L, Jupp RA, Isidoro C, Norey CG, Autelli R, Richards AD, Baccino FM
|
|
Title
|
Purification and properties of cathepsin D from rat Yoshida ascites hepatoma AH-130.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[2]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
2512908
|
|
Journal
|
Biochem J
|
|
Year
|
1989
|
|
Volume
|
263
|
|
Pages
|
601-4
|
|
Authors
|
Conner GE
|
|
Title
|
Isolation of procathepsin D from mature cathepsin D by pepstatin affinity chromatography. Autocatalytic proteolysis of the zymogen form of the enzyme.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[3]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
2002505
|
|
Journal
|
J Mol Biol
|
|
Year
|
1991
|
|
Volume
|
218
|
|
Pages
|
21-2
|
|
Authors
|
Baudys M, Ghosh M, Harlos K, Mares M, Fusek M, Kostka V, Blake CC
|
|
Title
|
Crystallization and preliminary crystallographic study of cathepsin D inhibitor from potatoes.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[4]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
1331083
|
|
Journal
|
J Biol Chem
|
|
Year
|
1992
|
|
Volume
|
267
|
|
Pages
|
23357-63
|
|
Authors
|
Cantor AB, Kornfeld S
|
|
Title
|
Phosphorylation of Asn-linked oligosaccharides located at novel sites on the lysosomal enzyme cathepsin D.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[5]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
1433300
|
|
Journal
|
J Mol Biol
|
|
Year
|
1992
|
|
Volume
|
227
|
|
Pages
|
1265-8
|
|
Authors
|
Bieber F, Brachvogel V, Arni R, Fusek M, Metcalf P
|
|
Title
|
Crystallization and initial crystallographic results for pepstatin A inhibited bovine cathepsin D.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[6]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
1640466
|
|
Journal
|
J Mol Biol
|
|
Year
|
1992
|
|
Volume
|
226
|
|
Pages
|
555-7
|
|
Authors
|
Fusek M, Baudys M, Metcalf P
|
|
Title
|
Purification and crystallization of human cathepsin D.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[7]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
1522590
|
|
Journal
|
J Mol Biol
|
|
Year
|
1992
|
|
Volume
|
227
|
|
Pages
|
265-70
|
|
Authors
|
Gulnik S, Baldwin ET, Tarasova N, Erickson J
|
|
Title
|
Human liver cathepsin D. Purification, crystallization and preliminary X-ray diffraction analysis of a lysosomal enzyme.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[8]
|
|
Resource
|
|
|
Comments
|
X-RAY CRYSTALLOGRAPHY (3 ANGSTROMS)
|
|
Medline ID
|
93223670
|
|
PubMed ID
|
8467789
|
|
Journal
|
EMBO J
|
|
Year
|
1993
|
|
Volume
|
12
|
|
Pages
|
1293-302
|
|
Authors
|
Metcalf P, Fusek M
|
|
Title
|
Two crystal structures for cathepsin D: the lysosomal targeting signal and active site.
|
|
Related PDB
|
|
|
Related UniProtKB
|
P07339
|
|
[9]
|
|
Resource
|
|
|
Comments
|
X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS)
|
|
Medline ID
|
93342076
|
|
PubMed ID
|
8393577
|
|
Journal
|
Proc Natl Acad Sci U S A
|
|
Year
|
1993
|
|
Volume
|
90
|
|
Pages
|
6796-800
|
|
Authors
|
Baldwin ET, Bhat TN, Gulnik S, Hosur MV, Sowder RC 2nd, Cachau RE, Collins J, Silva AM, Erickson JW
|
|
Title
|
Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design.
|
|
Related PDB
|
1lya
1lyb
|
|
Related UniProtKB
|
P07339
|
|
[10]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
8540315
|
|
Journal
|
Adv Exp Med Biol
|
|
Year
|
1995
|
|
Volume
|
362
|
|
Pages
|
155-66
|
|
Authors
|
Aguilar CF, Dhanaraj V, Guruprasad K, Dealwis C, Badasso M, Cooper JB, Wood SP, Blundell TL
|
|
Title
|
Comparisons of the three-dimensional structures, specificities and glycosylation of renins, yeast proteinase A and cathepsin D.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[11]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
8540317
|
|
Journal
|
Adv Exp Med Biol
|
|
Year
|
1995
|
|
Volume
|
362
|
|
Pages
|
181-92
|
|
Authors
|
Erickson JW, Baldwin ET, Bhat TN, Gulnik S
|
|
Title
|
Structure of human cathepsin D: comparison of inhibitor binding and subdomain displacement with other aspartic proteases.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[12]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
8540327
|
|
Journal
|
Adv Exp Med Biol
|
|
Year
|
1995
|
|
Volume
|
362
|
|
Pages
|
273-8
|
|
Authors
|
Koelsch G, Metcalf P, Vetvicka V, Fusek M
|
|
Title
|
Human procathepsin D: three-dimensional model and isolation.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[13]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
8540319
|
|
Journal
|
Adv Exp Med Biol
|
|
Year
|
1995
|
|
Volume
|
362
|
|
Pages
|
193-200
|
|
Authors
|
Metcalf P, Fusek M
|
|
Title
|
Cathepsin D crystal structures and lysosomal sorting.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[14]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
7657721
|
|
Journal
|
J Cell Sci
|
|
Year
|
1995
|
|
Volume
|
108
|
|
Pages
|
2007-15
|
|
Authors
|
Schorey JS, Fortenberry SC, Chirgwin JM
|
|
Title
|
Lysine residues in the C-terminal lobe and lysosomal targeting of procathepsin D.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[15]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
8663051
|
|
Journal
|
J Biol Chem
|
|
Year
|
1996
|
|
Volume
|
271
|
|
Pages
|
15590-6
|
|
Authors
|
Beyer BM, Dunn BM
|
|
Title
|
Self-activation of recombinant human lysosomal procathepsin D at a newly engineered cleavage junction, "short" pseudocathepsin D.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[16]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
9195867
|
|
Journal
|
Chem Biol
|
|
Year
|
1997
|
|
Volume
|
4
|
|
Pages
|
297-307
|
|
Authors
|
Kick EK, Roe DC, Skillman AG, Liu G, Ewing TJ, Sun Y, Kuntz ID, Ellman JA
|
|
Title
|
Structure-based design and combinatorial chemistry yield low nanomolar inhibitors of cathepsin D.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[17]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
9232647
|
|
Journal
|
Protein Sci
|
|
Year
|
1997
|
|
Volume
|
6
|
|
Pages
|
1458-66
|
|
Authors
|
Majer P, Collins JR, Gulnik SV, Erickson JW
|
|
Title
|
Structure-based subsite specificity mapping of human cathepsin D using statine-based inhibitors.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[18]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
9561243
|
|
Journal
|
Adv Exp Med Biol
|
|
Year
|
1998
|
|
Volume
|
436
|
|
Pages
|
363-73
|
|
Authors
|
Silva AM, Lee AY, Erickson JW, Goldberg DE
|
|
Title
|
Structural analysis of plasmepsin II. A comparison with human aspartic proteases.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[19]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
9694859
|
|
Journal
|
J Biol Chem
|
|
Year
|
1998
|
|
Volume
|
273
|
|
Pages
|
21067-76
|
|
Authors
|
Cuozzo JW, Tao K, Cygler M, Mort JS, Sahagian GG
|
|
Title
|
Lysine-based structure responsible for selective mannose phosphorylation of cathepsin D and cathepsin L defines a common structural motif for lysosomal enzyme targeting.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[20]
|
|
Resource
|
|
|
Comments
|
X-ray crystallography
|
|
Medline ID
|
|
|
PubMed ID
|
9783744
|
|
Journal
|
Nat Struct Biol
|
|
Year
|
1998
|
|
Volume
|
5
|
|
Pages
|
866-71
|
|
Authors
|
Lee AY, Gulnik SV, Erickson JW
|
|
Title
|
Conformational switching in an aspartic proteinase.
|
|
Related PDB
|
1lyw
|
|
Related UniProtKB
|
|
|
[21]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
9514263
|
|
Journal
|
Protein Sci
|
|
Year
|
1998
|
|
Volume
|
7
|
|
Pages
|
88-95
|
|
Authors
|
Beyer BM, Dunn BM
|
|
Title
|
Prime region subsite specificity characterization of human cathepsin D: the dominant role of position 128.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[22]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
9890884
|
|
Journal
|
Biochemistry
|
|
Year
|
1999
|
|
Volume
|
38
|
|
Pages
|
73-80
|
|
Authors
|
Lukong KE, Elsliger MA, Mort JS, Potier M, Pshezhetsky AV
|
|
Title
|
Identification of UDP-N-acetylglucosamine-phosphotransferase-binding sites on the lysosomal proteases, cathepsins A, B, and D.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[23]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
11731271
|
|
Journal
|
Matrix Biol
|
|
Year
|
2001
|
|
Volume
|
20
|
|
Pages
|
543-53
|
|
Authors
|
Handley CJ, Mok MT, Ilic MZ, Adcocks C, Buttle DJ, Robinson HC
|
|
Title
|
Cathepsin D cleaves aggrecan at unique sites within the interglobular domain and chondroitin sulfate attachment regions that are also cleaved when cartilage is maintained at acid pH.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[24]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
11687971
|
|
Journal
|
Oncogene
|
|
Year
|
2001
|
|
Volume
|
20
|
|
Pages
|
6920-9
|
|
Authors
|
Glondu M, Coopman P, Laurent-Matha V, Garcia M, Rochefort H, Liaudet-Coopman E
|
|
Title
|
A mutated cathepsin-D devoid of its catalytic activity stimulates the growth of cancer cells.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[25]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
11906282
|
|
Journal
|
J Med Chem
|
|
Year
|
2002
|
|
Volume
|
45
|
|
Pages
|
1412-9
|
|
Authors
|
Huo S, Wang J, Cieplak P, Kollman PA, Kuntz ID
|
|
Title
|
Molecular dynamics and free energy analyses of cathepsin D-inhibitor interactions: insight into structure-based ligand design.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[26]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
12350228
|
|
Journal
|
Biochem J
|
|
Year
|
2003
|
|
Volume
|
369
|
|
Pages
|
55-62
|
|
Authors
|
Partanen S, Storch S, Loffler HG, Hasilik A, Tyynela J, Braulke T
|
|
Title
|
A replacement of the active-site aspartic acid residue 293 in mouse cathepsin D affects its intracellular stability, processing and transport in HEK-293 cells.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
|
[27]
|
|
Resource
|
|
|
Comments
|
|
|
Medline ID
|
|
|
PubMed ID
|
14695825
|
|
Journal
|
J Med Chem
|
|
Year
|
2004
|
|
Volume
|
47
|
|
Pages
|
110-22
|
|
Authors
|
Ersmark K, Feierberg I, Bjelic S, Hamelink E, Hackett F, Blackman MJ, Hulten J, Samuelsson B, Aqvist J, Hallberg A
|
|
Title
|
Potent inhibitors of the Plasmodium falciparum enzymes plasmepsin I and II devoid of cathepsin D inhibitory activity.
|
|
Related PDB
|
|
|
Related UniProtKB
|
|
