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| Medline ID |  | 
| PubMed ID | 3182871 | 
| Journal | J Biol Chem | 
| Year | 1988 | 
| Volume | 263 | 
| Pages | 17828-36 | 
| Authors | Gardell SJ, Craik CS, Clauser E, Goldsmith EJ, Stewart CB, Graf M, Rutter WJ | 
| Title | A novel rat carboxypeptidase, CPA2: characterization, molecular cloning, and evolutionary implications on substrate specificity in the carboxypeptidase gene family. | 
| Related PDB |  | 
| Related UniProtKB |  | 
| [2] | 
| Resource |  | 
| Comments |  | 
| Medline ID |  | 
| PubMed ID | 2920728 | 
| Journal | Eur J Biochem | 
| Year | 1989 | 
| Volume | 179 | 
| Pages | 609-16 | 
| Authors | Pascual R, Burgos FJ, Salva M, Soriano F, Mendez E, Aviles FX | 
| Title | Purification and properties of five different forms of human procarboxypeptidases. | 
| Related PDB |  | 
| Related UniProtKB |  | 
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| Medline ID |  | 
| PubMed ID | 1761558 | 
| Journal | J Biol Chem | 
| Year | 1991 | 
| Volume | 266 | 
| Pages | 24606-12 | 
| Authors | Faming Z, Kobe B, Stewart CB, Rutter WJ, Goldsmith EJ | 
| Title | Structural evolution of an enzyme specificity. The structure of rat carboxypeptidase A2 at 1.9-A resolution. | 
| Related PDB |  | 
| Related UniProtKB |  | 
| [4] | 
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| Comments |  | 
| Medline ID |  | 
| PubMed ID | 8436102 | 
| Journal | Eur J Biochem | 
| Year | 1993 | 
| Volume | 211 | 
| Pages | 381-9 | 
| Authors | Aviles FX, Vendrell J, Guasch A, Coll M, Huber R | 
| Title | Advances in metallo-procarboxypeptidases. Emerging details on the inhibition mechanism and on the activation process. | 
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| Medline ID |  | 
| PubMed ID | 8200353 | 
| Journal | Eur J Biochem | 
| Year | 1994 | 
| Volume | 222 | 
| Pages | 55-63 | 
| Authors | Oppezzo O, Ventura S, Bergman T, Vendrell J, Jornvall H, Aviles FX | 
| Title | Procarboxypeptidase in rat pancreas. Overall characterization and comparison of the activation processes. | 
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| PubMed ID | 7896805 | 
| Journal | J Biol Chem | 
| Year | 1995 | 
| Volume | 270 | 
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| Authors | Catasus L, Vendrell J, Aviles FX, Carreira S, Puigserver A, Billeter M | 
| Title | The sequence and conformation of human pancreatic procarboxypeptidase A2. cDNA cloning, sequence analysis, and three-dimensional model. | 
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| Comments | X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS). | 
| Medline ID | 98046021 | 
| PubMed ID | 9384570 | 
| Journal | EMBO J | 
| Year | 1997 | 
| Volume | 16 | 
| Pages | 6906-13 | 
| Authors | Garcia-Saez I, Reverter D, Vendrell J, Aviles FX, Coll M | 
| Title | The three-dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen. | 
| Related PDB | 1aye | 
| Related UniProtKB | P48052 | 
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| Comments | X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS). | 
| Medline ID | 98111000 | 
| PubMed ID | 9450539 | 
| Journal | FEBS Lett | 
| Year | 1997 | 
| Volume | 420 | 
| Pages | 7-10 | 
| Authors | Reverter D, Garcia-Saez I, Catasus L, Vendrell J, Coll M, Aviles FX | 
| Title | Characterisation and preliminary X-ray diffraction analysis of human pancreatic procarboxypeptidase A2. | 
| Related PDB |  | 
| Related UniProtKB | P48052 | 
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| Medline ID |  | 
| PubMed ID | 9524066 | 
| Journal | Biol Chem | 
| Year | 1998 | 
| Volume | 379 | 
| Pages | 149-55 | 
| Authors | Aloy P, Catasus L, Villegas V, Reverter D, Vendrell J, Aviles FX | 
| Title | Comparative analysis of the sequences and three-dimensional models of human procarboxypeptidases A1, A2 and B. | 
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| PubMed ID | 9452479 | 
| Journal | J Biol Chem | 
| Year | 1998 | 
| Volume | 273 | 
| Pages | 3535-41 | 
| Authors | Reverter D, Ventura S, Villegas V, Vendrell J, Aviles FX | 
| Title | Overexpression of human procarboxypeptidase A2 in Pichia pastoris and detailed characterization of its activation pathway. | 
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| Medline ID |  | 
| PubMed ID | 9799641 | 
| Journal | J Mol Biol | 
| Year | 1998 | 
| Volume | 283 | 
| Pages | 1027-36 | 
| Authors | Villegas V, Martinez JC, Aviles FX, Serrano L | 
| Title | Structure of the transition state in the folding process of human procarboxypeptidase A2 activation domain. | 
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| Related UniProtKB |  | 
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| Medline ID |  | 
| PubMed ID | 10542090 | 
| Journal | Nat Struct Biol | 
| Year | 1999 | 
| Volume | 6 | 
| Pages | 1005-9 | 
| Authors | Chiti F, Taddei N, White PM, Bucciantini M, Magherini F, Stefani M, Dobson CM | 
| Title | Mutational analysis of acylphosphatase suggests the importance of topology and contact order in protein folding. | 
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| PubMed ID | 10201391 | 
| Journal | Nat Struct Biol | 
| Year | 1999 | 
| Volume | 6 | 
| Pages | 304-7 | 
| Authors | Ionescu RM, Matthews CR | 
| Title | Folding under the influence. | 
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| PubMed ID | 10708864 | 
| Journal | Biochim Biophys Acta | 
| Year | 2000 | 
| Volume | 1477 | 
| Pages | 284-98 | 
| Authors | Vendrell J, Querol E, Aviles FX | 
| Title | Metallocarboxypeptidases and their protein inhibitors. Structure, function and biomedical properties. | 
| Related PDB |  | 
| Related UniProtKB |  | 
| [15] | 
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| Medline ID |  | 
| PubMed ID | 10998048 | 
| Journal | Eur J Biochem | 
| Year | 2000 | 
| Volume | 267 | 
| Pages | 5891-9 | 
| Authors | Fernandez AM, Villegas V, Martinez JC, Van Nuland NA, Conejero-Lara F, Aviles FX, Serrano L, Filimonov VV, Mateo PL | 
| Title | Thermodynamic analysis of helix-engineered forms of the activation domain of human procarboxypeptidase A2. | 
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| Related UniProtKB |  | 
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| PubMed ID | 10781799 | 
| Journal | FEBS Lett | 
| Year | 2000 | 
| Volume | 472 | 
| Pages | 27-33 | 
| Authors | Villanueva J, Canals F, Villegas V, Querol E, Aviles FX | 
| Title | Hydrogen exchange monitored by MALDI-TOF mass spectrometry for rapid characterization of the stability and conformation of proteins. | 
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| [17] | 
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| Comments |  | 
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| PubMed ID | 10702927 | 
| Journal | J Comput Aided Mol Des | 
| Year | 2000 | 
| Volume | 14 | 
| Pages | 83-92 | 
| Authors | Aloy P, Mas JM, Marti-Renom MA, Querol E, Aviles FX, Oliva B | 
| Title | Refinement of modelled structures by knowledge-based energy profiles and secondary structure prediction: application to the human procarboxypeptidase A2. | 
| Related PDB |  | 
| Related UniProtKB |  | 
| [18] | 
| Resource |  | 
| Comments | X-ray crystallography | 
| Medline ID |  | 
| PubMed ID | 10742178 | 
| Journal | Nat Struct Biol | 
| Year | 2000 | 
| Volume | 7 | 
| Pages | 322-8 | 
| Authors | Reverter D, Fernandez-Catalan C, Baumgartner R, Pfander R, Huber R, Bode W, Vendrell J, Holak TA, Aviles FX | 
| Title | Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2. | 
| Related PDB | 1dtd | 
| Related UniProtKB |  | 
| [19] | 
| Resource |  | 
| Comments |  | 
| Medline ID |  | 
| PubMed ID | 11045616 | 
| Journal | Protein Sci | 
| Year | 2000 | 
| Volume | 9 | 
| Pages | 1700-8 | 
| Authors | Villegas V, Zurdo J, Filimonov VV, Aviles FX, Dobson CM, Serrano L | 
| Title | Protein engineering as a strategy to avoid formation of amyloid fibrils. | 
| Related PDB |  | 
| Related UniProtKB |  | 
| [20] | 
| Resource |  | 
| Comments |  | 
| Medline ID |  | 
| PubMed ID | 12271440 | 
| Journal | J Mass Spectrom | 
| Year | 2002 | 
| Volume | 37 | 
| Pages | 974-84 | 
| Authors | Villanueva J, Villegas V, Querol E, Aviles FX, Serrano L | 
| Title | Protein secondary structure and stability determined by combining exoproteolysis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. | 
| Related PDB |  | 
| Related UniProtKB |  | 
| [21] | 
| Resource |  | 
| Comments | NMR, 20 Structures | 
| Medline ID |  | 
| PubMed ID | 12538893 | 
| Journal | Protein Sci | 
| Year | 2003 | 
| Volume | 12 | 
| Pages | 296-305 | 
| Authors | Jimenez MA, Villegas V, Santoro J, Serrano L, Vendrell J, Aviles FX, Rico M | 
| Title | NMR solution structure of the activation domain of human procarboxypeptidase A2. | 
| Related PDB | 1o6x | 
| Related UniProtKB |  |