R L C P
Hierarchic Classification of Catalytic Mechanisms

R 8.-.-.- : Isomerization (shift of double-bond position) (Reaction)

L 8.113.-.- : Adjacent bond; C=C-O to C-C=O (Ligand group involved)

Catalytic mechanisms

8.113.42001.- : Base-Acid/Stabilizers; Base deprotonation of initially single-bonded atom leading to intermediate formation; Intermediate stabilized; Acid protonation to initially double-bonded atom

8.113.46500.- : Metal-independent eukaryotic CMLE-like mechanism (Acid/Base); Base deprotonation of initially single-bonded atom & Acid protonation to initially double-bonded atom

8.113.365000.- : Acid/Modulator; Modulator-assisted acid protonation to initially-double-bonded atom; water molecules required for proton shuttle to recover catalytic residues

8.113.365001.- : Acid/Modulator; Modulator-assisted acid protonation to initially-double-bonded atom through a water; water molecules required for proton shuttle to recover catalytic residues

8.113.580000.- : Base-Stabilizer/Acid/Modulator/Stabilizer; Inorganic cofactor-assisted stabilization of adjacent atoms of central atom/initially single-bonded atom/double-bonded atom; Modulator-assisted acid protonation to initially double-bonded atom & Base deprotonation of initially single-bonded atom

8.113.585900.- : Acid-Base/Acid; Inorganic-cofactor-assisted stabilization of initially single-bonded atom and adjacent atom to double-bonded atom; Acid protonation to double-bonded atom & Base deprotonation of single-bonded atom; 2nd Acid protonation to adjacent atom to initially-double-bonded atom

8.113.594730.- : Metal-dependent bacterial MLE-like mechanism(Acid/Base/Stabilizer); Inorganic-cofactor-assisted stabilization of single-bonded atom; Acid protonation to single-bonded atom & Base deprotonation from double-bonded atom

8.113.901890.- : Glucarate dehydratase 3rd reaction step-like mechanism (Acid/Stabilizer); Catalytic-residue-stabilization of Single-bonded atom and inorganic-cofactor-assisted stabilization of functional group bonded to central atom; Acid protonation to double-bonded atom

8.113.904850.- : 6-phospho-alpha-glucosidase 5th reaction step-like mechanism (Acid/Modulator); Modulator-assisted acid through water & Inorganic cofactor stabilization of initially single-bonded atom and adjacent atom to initially double-bonded atom; Acid protonation of initially double-bonded atom

8.113.904870.- : Mannose-6-phosphate isomerase 2nd reaction step-like mechanism (Acid/Modulator); Inorganic-cofacotor stabilization of initially single-bonded atom; Modulator-assisted acid protonation to initially double-bonded atom

8.113.915300.- : Acid/Stabilizer; Inorganic-cofactor-assisted stabilization of initially single-bonded atom; Acid protonation to double-bonded atom

8.113.915310.- : Acid/Proton_shuttle/Stabilizer; Inorganic-cofactor-assisted stabilization of initially single-bonded atom; Acid protonation to double-bonded atom through proton-shuttle

8.113.919760.- : Acid; Inorganic-cofactor-assisted stabilization of initially single-bonded atom; Acid protonation to double-bonded atom

8.113.1441400.- : GDP fucose synthase 2nd reaction step-like mechanism (Acid/Stabilizer/Modulator); Modulation of Stabilizer through inorganic-cofactor; Stabilization of initially single-bonded atom; Acid protonation to initially double-bonded atom