RLCP 8.113.904870.- :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms


R 8.-.-.- : Isomerization (shift of double-bond position) (Reaction)

L 8.113.-.- : Adjacent bond; C=C-O to C-C=O (Ligand group involved)

C 8.113.904870.- : Mannose-6-phosphate isomerase 2nd reaction step-like mechanism (Acid/Modulator); Inorganic-cofacotor stabilization of initially single-bonded atom; Modulator-assisted acid protonation to initially double-bonded atom (Catalytic mechanism)

1st Nucleophile : non-existent
Catalytic groups : cofactor + groups in residue/substrate
General Base : non-existent
General Acid : a catalytic residue

Residues/Cofactors involved in Proteins

  • 8.113.904870.263 : Glu/Tyr + zinc ion bound to His/Glu/Gln cluster

    • Copyright: Nozomi Nagano, JST & CBRC-AIST
    Funded by PRESTO/Japan Science and Technology Agency (JST) (December 2001 - November 2004)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2006)
    Funded by Grant-in-Aid for Scientific Research (B)/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (September 2005 - September 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (October 2007 - September 2010)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2011 - March 2012)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2012 - March 2013)
    Supported by the commission for the Development of Artificial Gene Synthesis Technology for Creating Innovative Biomaterial from the Ministry of Economy, Trade and Industry (METI) (October 2012 - March 2016)
    Funded by the project commissioned by the New Energy and Industrial Technology Development Organization (NEDO) (April 2016 -)