RLCP 6.40.508000.5522 :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms


R 6.-.-.- : Exchange of double-bonded atoms (Schiff-base related reaction) (Reaction)

L 6.40.-.- : Exchange of Schiff-base nitrogen atoms (internal aldimine formation) (Ligand group involved)

C 6.40.508000.- : Nucleophile/Acid/Modulator; Nucleophile attacks on double-bond partner atom; Formation of tetrahedral intermediate; Organic-cofactor-assisted protonation to leaving group & deprotonation of nucleophile; Lone pair on nucleophile attacks on double-bond partner atom (Catalytic mechanism)

P 6.40.508000.5522 : Lys/Tyr +Arg/His/Asp + PLP double-bonded to substrate/intermediate (Residues/cofactors in Protein)

1st Nucleophile : a catalytic residue
Catalytic groups : cofactor + groups in residue/substrate
General Base : a group in substrate/cofactor
General Acid : a group in substrate/cofactor

Related Enzymes

There is one entry in this class.
  • D00271 : (reaction 4) 5.1.1.1; Alanine racemase (Catalytic domains; 2.40.37.10, 3.20.20.10)
    • Copyright: Nozomi Nagano, JST & CBRC-AIST
    Funded by PRESTO/Japan Science and Technology Agency (JST) (December 2001 - November 2004)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2006)
    Funded by Grant-in-Aid for Scientific Research (B)/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (September 2005 - September 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (October 2007 - September 2010)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2011 - March 2012)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2012 - March 2013)
    Supported by the commission for the Development of Artificial Gene Synthesis Technology for Creating Innovative Biomaterial from the Ministry of Economy, Trade and Industry (METI) (October 2012 - March 2016)
    Funded by the project commissioned by the New Energy and Industrial Technology Development Organization (NEDO) (April 2016 -)