RLCP 1.30.300.2 :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms


R 1.-.-.- : Hydrolysis (bond cleavage by water) (Reaction)

L 1.30.-.- : C-O bond (O-glycoside bond) (Ligand group involved)

C 1.30.300.- : Exoglucanase-II-like mechanism (Acid/Base); Base-activated water directly attacks on substrate & hydrolysis assisted by proton donor (SN2) (Catalytic mechanism)

P 1.30.300.2 : Two acidic residues (Residues/cofactors in Protein)

1st Nucleophile : water
Catalytic groups : groups in residue/substrate
General Base : a catalytic residue
General Acid : a catalytic residue

Related Enzymes

There are 5 entries in this class.
  • S00021 : 3.2.1.17; Lysozyme (Catalytic domain; 1.10.530.40)
  • S00194 : 3.2.1.4; Endoglucanase-6B (Catalytic domain; 3.20.20.40)
  • S00265 : 3.2.1.132; Chitosanase (Catalytic domain; 1.10.530.40)
  • D00536 : 3.2.1.4; Endoglucanase E-2 (Catalytic domain; 3.20.20.40)
  • D00537 : 3.2.1.91; Exoglucanase 2 (Catalytic domain; 3.20.20.40)
    • Copyright: Nozomi Nagano, JST & CBRC-AIST
    Funded by PRESTO/Japan Science and Technology Agency (JST) (December 2001 - November 2004)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2006)
    Funded by Grant-in-Aid for Scientific Research (B)/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (September 2005 - September 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (October 2007 - September 2010)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2011 - March 2012)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2012 - March 2013)
    Supported by the commission for the Development of Artificial Gene Synthesis Technology for Creating Innovative Biomaterial from the Ministry of Economy, Trade and Industry (METI) (October 2012 - March 2016)
    Funded by the project commissioned by the New Energy and Industrial Technology Development Organization (NEDO) (April 2016 -)