RLCP 4.16.66400.7 :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms


R 4.-.-.- : Addition to double-bond (new bond formation and decreased bond-order) (Reaction)

L 4.16.-.- : Water (H2O; hydration) to sp2-like Carbon (C=O-PO3) [leading to HO-C-OPO3] (Ligand group involved)

C 4.16.66400.- : Base/Base; Base deprotonation of added group; Activated added group attacks on addition site of unsaturated group; 2nd base deprotonation of protonated 1st base (Catalytic mechanism)

P 4.16.66400.7 : An acidic residue + Lys (Residues/cofactors in Protein)


1st Nucleophile : Added group (substrate or water)
Catalytic groups : groups in residue/substrate
General Base : a catalytic residue
General Acid : non-existent

Related Enzymes

There is one entry in this class.
  • S00243 : (reaction 2) 2.5.1.54; Phospho-2-dehydro-3-deoxyheptonate aldolase (Catalytic domain; 3.20.20.70)
  • Copyright: Nozomi Nagano, JST & CBRC-AIST
    Funded by PRESTO/Japan Science and Technology Agency (JST) (December 2001 - November 2004)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2006)
    Funded by Grant-in-Aid for Scientific Research (B)/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (September 2005 - September 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (October 2007 - September 2010)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2011 - March 2012)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2012 - March 2013)
    Supported by the commission for the Development of Artificial Gene Synthesis Technology for Creating Innovative Biomaterial from the Ministry of Economy, Trade and Industry (METI) (October 2012 - March 2016)
    Funded by the project commissioned by the New Energy and Industrial Technology Development Organization (NEDO) (April 2016 -)