RLCP 4.1010.695600.- :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms


R 4.-.-.- : Addition to double-bond (new bond formation and decreased bond-order) (Reaction)

L 4.1010.-.- : Water (H2O; hydration) to Carbon (sp2) adjacent to double-bond; Opposition to non-beta-elimination (Ligand group involved)

C 4.1010.695600.- : 6-phospho-alpha-glucosidase 4th reaction step-like mechanism (Base); Inorganic cofactor-assisted stabilization of protonation site of unsaturated group; Base deprotonation of added group; Added group attacks on addition site of unsaturated group (Catalytic mechanism)

1st Nucleophile : Added group (substrate or water)
Catalytic groups : cofactor + groups in residue/substrate
General Base : a catalytic residue
General Acid : non-existent

Residues/Cofactors involved in Proteins

  • 4.1010.695600.8301 : An acidic residue + manganese ion bound to Cys/His/O7-nicotinamide/substrate or intermediate

    • Copyright: Nozomi Nagano, JST & CBRC-AIST
    Funded by PRESTO/Japan Science and Technology Agency (JST) (December 2001 - November 2004)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2006)
    Funded by Grant-in-Aid for Scientific Research (B)/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (September 2005 - September 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (October 2007 - September 2010)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2011 - March 2012)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2012 - March 2013)
    Supported by the commission for the Development of Artificial Gene Synthesis Technology for Creating Innovative Biomaterial from the Ministry of Economy, Trade and Industry (METI) (October 2012 - March 2016)
    Funded by the project commissioned by the New Energy and Industrial Technology Development Organization (NEDO) (April 2016 -)