RLCP 3.1147.900.95 :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms


R 3.-.-.- : Transfer (bond cleavage and new bond formation) (Reaction)

L 3.1147.-.- : Acyl group from Sulfur atom to Amine nitrogen (sp3) (Ligand group involved)

C 3.1147.900.- : Serotonin N-acetyltransferase-like mechanism (Acid/Base/Proton_shuttle/Stabilizer); Base-activation of acceptor group through proton_shuttle and water; SN2-like nucleophilic attack on transferred group by acceptor group; Transition state stabilized; Acid protonation to leaving group (Catalytic mechanism)

P 3.1147.900.95 : Tyr/His/His + mainchain amide (Residues/cofactors in Protein)

1st Nucleophile : an acceptor group in substrate
Catalytic groups : groups in residue/substrate
General Base : a catalytic residue
General Acid : a catalytic residue

Related Enzymes

There is one entry in this class.
  • S00410 : 2.3.1.87; Serotonin N-acetyltransferase (Catalytic domain; 3.40.630.30)
    • Copyright: Nozomi Nagano, JST & CBRC-AIST
    Funded by PRESTO/Japan Science and Technology Agency (JST) (December 2001 - November 2004)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2006)
    Funded by Grant-in-Aid for Scientific Research (B)/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (September 2005 - September 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (October 2007 - September 2010)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2011 - March 2012)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2012 - March 2013)
    Supported by the commission for the Development of Artificial Gene Synthesis Technology for Creating Innovative Biomaterial from the Ministry of Economy, Trade and Industry (METI) (October 2012 - March 2016)
    Funded by the project commissioned by the New Energy and Industrial Technology Development Organization (NEDO) (April 2016 -)