RLCP 3.100.790.76 :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms


R 3.-.-.- : Transfer (bond cleavage and new bond formation) (Reaction)

L 3.100.-.- : Phosphate group from Hydroxyl oxygen to Hydroxyl oxygen (Ligand group involved)

C 3.100.790.- : Bacterial PI-PLC-like mechanism (Base/Acid/Modulator/Stabilizer); SN2-like reaction; Modulator-assisted base activation of acceptor group; Nucleophilic attack on transferred group by activated acceptor group; Stablization of transition state & Modulator-assisted acid protonation to leaving group (Catalytic mechanism)

P 3.100.790.76 : His/His + acidic residues + Arg (Residues/cofactors in Protein)

1st Nucleophile : an acceptor group in substrate
Catalytic groups : groups in residue/substrate
General Base : a catalytic residue
General Acid : a catalytic residue

Related Enzymes

There is one entry in this class.
  • S00236 : 4.6.1.13; 1-phosphatidylinositol phosphodiesterase (Catalytic domain; 3.20.20.190)
    • Copyright: Nozomi Nagano, JST & CBRC-AIST
    Funded by PRESTO/Japan Science and Technology Agency (JST) (December 2001 - November 2004)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2006)
    Funded by Grant-in-Aid for Scientific Research (B)/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (September 2005 - September 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (October 2007 - September 2010)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2011 - March 2012)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2012 - March 2013)
    Supported by the commission for the Development of Artificial Gene Synthesis Technology for Creating Innovative Biomaterial from the Ministry of Economy, Trade and Industry (METI) (October 2012 - March 2016)
    Funded by the project commissioned by the New Energy and Industrial Technology Development Organization (NEDO) (April 2016 -)