RLCP 1.14.36110.975 :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms


R 1.-.-.- : Hydrolysis (bond cleavage by water) (Reaction)

L 1.14.-.- : Thioester (One of Carbonyl Ester bonds) (Ligand group involved)

C 1.14.36110.- : 4-hydroxybenzoyl-CoA thioesterase-like mechanism (Nucleophile/Acid-Base/Stabilizer); SN1-like reaction induced by stabilizer; covalent bond formation between nucleophile and target atom; Acid protonation to leaving group; intermediate stablilized; covalent bond attacked by base-activated water; intermediate stabilized (Catalytic mechanism)

P 1.14.36110.975 : Two acidic residues + mainchain amide (Residues/cofactors in Protein)

1st Nucleophile : a catalytic residue
Catalytic groups : groups in residue/substrate
General Base : a catalytic residue
General Acid : a catalytic residue

Related Enzymes

There is one entry in this class.
  • S00179 : 3.1.2.23; 4-hydroxybenzoyl-CoA thioesterase (Catalytic domain; 3.10.129.10)
    • Copyright: Nozomi Nagano, JST & CBRC-AIST
    Funded by PRESTO/Japan Science and Technology Agency (JST) (December 2001 - November 2004)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2006)
    Funded by Grant-in-Aid for Scientific Research (B)/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (September 2005 - September 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (October 2007 - September 2010)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2011 - March 2012)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2012 - March 2013)
    Supported by the commission for the Development of Artificial Gene Synthesis Technology for Creating Innovative Biomaterial from the Ministry of Economy, Trade and Industry (METI) (October 2012 - March 2016)
    Funded by the project commissioned by the New Energy and Industrial Technology Development Organization (NEDO) (April 2016 -)