This enzyme has got a second coenzyme subsite for NAD(P), which seems to be involved in regulation.
Leucine Dehydrogenase; Chain A, domain 1
Studies of glutamate dehydrogenase: chemical modification and quantitative determination of tryptophan residues.
The demonstration of a glutamate dehydrogenase-NADP-L-glutamate charge-transfer complex and its location on the reaction pathway.
Crystallization and characterization of bovine liver glutamate dehydrogenase.
Identification and characterization of kinetically competent carbinolamine and alpha-iminoglutarate complexes in the glutamate dehydrogenase-catalyzed oxidation of L-glutamate using a multiwavelength transient state approach.
Photoaffinity labeling of brain glutamate dehydrogenase isoproteins with an azido-ADP.
The structure of bovine glutamate dehydrogenase provides insights into the mechanism of allostery.
Stabilization of noncovalent intermediates in enzymatically catalyzed reactions.
Adenosine 5'-0-[S-(4-succinimidyl-benzophenone)thiophosphate]: a new photoaffinity label of the allosteric ADP site of bovine liver glutamate dehydrogenase.
Cassette mutagenesis of lysine 130 of human glutamate dehydrogenase. An essential residue in catalysis.
Octyl glucoside induced formation of the molten globule-like state of glutamate dehydrogenase.
Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation.
Substitution of Ser for Arg-443 in the regulatory domain of human housekeeping (GLUD1) glutamate dehydrogenase virtually abolishes basal activity and markedly alters the activation of the enzyme by ADP and L-leucine.
Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme.
The structure of apo human glutamate dehydrogenase details subunit communication and allostery.
Catalytic activity of bovine glutamate dehydrogenase requires a hexamer structure.
Carbonyl oxygen exchange evidence of imine formation in the glutamate dehydrogenase reaction and identification of the "occult role" of NADPH.
A transfer nuclear Overhauser effect study of coenzyme binding to distinct sites in binary and ternary complexes in glutamate dehydrogenase.
Reversible association of ox liver glutamate dehydrogenase with the inner mitochondrial membrane.
Multiple interactions of lysine-128 of Escherichia coli glutamate dehydrogenase revealed by site-directed mutagenesis studies.
Enzymatic in situ analysis by 1H-NMR of the hydrogen transfer stereospecificity of NAD(P)+-dependent dehydrogenases.
Transduction of enzyme-ligand binding energy into catalytic driving force.