This enzyme belongs to the LDH famiyl in the LDH/MDH superfamily.
L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2
Atomic co-ordinates for dogfish M4 apo-lactate dehydrogenase.
D-lactate dehydrogenase. Substrate specificity and use as a catalyst in the synthesis of homochiral 2-hydroxy acids.
Structure determination and refinement of Bacillus stearothermophilus lactate dehydrogenase.
Design and synthesis of new enzymes based on the lactate dehydrogenase framework.
Structure of a ternary complex of an allosteric lactate dehydrogenase from Bacillus stearothermophilus at 2.5 A resolution.
Charge balance in the alpha-hydroxyacid dehydrogenase vacuole: an acid test.
Molecular basis of allosteric activation of bacterial L-lactate dehydrogenase.
Crystal structure of a NAD-dependent D-glycerate dehydrogenase at 2.4 A resolution.
T and R states in the crystals of bacterial L-lactate dehydrogenase reveal the mechanism for allosteric control.
Identifying the mechanism of protein loop closure: a molecular dynamics simulation of the Bacillus stearothermophilus LDH loop in solution.
The structure of lactate dehydrogenase from Plasmodium falciparum reveals a new target for anti-malarial design.
A comparison of the structures of apo dogfish M4 lactate dehydrogenase and its ternary complexes.
Molecular dynamics simulations of N-terminal peptides from a nucleotide binding protein.
The contribution of electrostatic and van der Waals interactions to the stereospecificity of the reaction catalyzed by lactate dehydrogenase.
Correlation of the enzyme activities of Bacillus stearothermophilus lactate dehydrogenase on three substrates with the results of molecular dynamics/energy minimization conformational searching.
Chloroquine binds in the cofactor binding site of Plasmodium falciparum lactate dehydrogenase.
Redesign of the coenzyme specificity in L-lactate dehydrogenase from bacillus stearothermophilus using site-directed mutagenesis and media engineering.
epsilon-crystallin from duck eye lens comparison of its quaternary structure and stability with other lactate dehydrogenases and complex formation with alpha-crystallin.
The A245K mutation exposes another stage of the bacterial L-lactate dehydrogenase reaction mechanism.
Crystal structure of the MJ0490 gene product of the hyperthermophilic archaebacterium Methanococcus jannaschii, a novel member of the lactate/malate family of dehydrogenases.
Structural basis for altered activity of M- and H-isozyme forms of human lactate dehydrogenase.
Structural adaptations of lactate dehydrogenase isozymes.
Crystal structure of non-allosteric L-lactate dehydrogenase from Lactobacillus pentosus at 2.3 A resolution: specific interactions at subunit interfaces.
Crystal structure of Plasmodium berghei lactate dehydrogenase indicates the unique structural differences of these enzymes are shared across the Plasmodium genus.
Comparative structural analysis and kinetic properties of lactate dehydrogenases from the four species of human malarial parasites.
Identification and activity of a series of azole-based compounds with lactate dehydrogenase-directed anti-malarial activity.
Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Structure of lactate dehydrogenase from Plasmodium vivax: complexes with NADH and APADH.
The structure of mouse testicular lactate dehydrogenase isoenzyme C4 at 2.9 A resolution.
Structure of the active ternary complex of pig heart lactate dehydrogenase with S-lac-NAD at 2.7 A resolution.
The complete primary structure of the allosteric L-lactate dehydrogenase from Lactobacillus casei.
Structure determination of the allosteric L-lactate dehydrogenase from Lactobacillus-casei at 3A resolution.
Characterization of the antigenic sites on the refined 3-A resolution structure of mouse testicular lactate dehydrogenase C4.
Refined crystal structure of dogfish M4 apo-lactate dehydrogenase.
Lactate dehydrogenase from the hyperthermophilic bacterium thermotoga maritima: the crystal structure at 2.1 A resolution reveals strategies for intrinsic protein stabilization.