THR 250(magnesium-1 binding);ASN 166;ASN 187;GLU 190(magnesium-2 binding);ASP 249;ILE 251;ALA 285;ARG 288;GLY 290;SER 294(potassium binding);ALA 170;ASN 187(orthophosphate binding)
Purification, characterization, and crystallization of Escherichia coli ribokinase.
X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) OF SHORT ISOFORM
Structure of human adenosine kinase at 1.5 A resolution.
Structure of Escherichia coli ribokinase in complex with ribose and dinucleotide determined to 1.8 A resolution: insights into a new family of kinase structures.
Errors and reproducibility in electron-density map interpretation.
Induced fit on sugar binding activates ribokinase.
X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) IN COMPLEX WITH SUBSTRATE, HOMOTRIMERIZATION, AND MUTAGENESIS OF CYS-198.
Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution.
Genetic and biochemical characterization of Salmonella enterica serovar typhi deoxyribokinase.
Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
The effect of inorganic phosphate on the activity of bacterial ribokinase.
X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) IN COMPLEX WITH ADP, AND SUBUNIT.
Structural basis for the ADP-specificity of a novel glucokinase from a hyperthermophilic archaeon.
Pentavalent ions dependency is a conserved property of adenosine kinase from diverse sources: identification of a novel motif implicated in phosphate and magnesium ion binding and substrate inhibition.
X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) IN COMPLEX WITH SUBSTRATE; ADP AND COFACTOR.
Crystal structure of brain pyridoxal kinase, a novel member of the ribokinase superfamily.
Activation of ribokinase by monovalent cations.
Structure of Bacillus subtilis YXKO--a member of the UPF0031 family and a putative kinase.
X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 23-266.
Crystal structure of 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase from Salmonella typhimurium at 2.3 A resolution.
X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) IN COMPLEX WITH AMP AND GLUCOSE, AND SUBUNIT.
Crystal structure of an ADP-dependent glucokinase from Pyrococcus furiosus: implications for a sugar-induced conformational change in ADP-dependent kinase.
International Journal of Molecular Sciences
The mechanism of phosphoryl transfer reaction and the role of active site residues on the basis of ribokinase-like kinases.
Crystal structure of the PdxY Protein from Escherichia coli.
Structure of Thermus thermophilus 2-Keto-3-deoxygluconate kinase: evidence for recognition of an open chain substrate.
Crystal structure of an aminoimidazole riboside kinase from Salmonella enterica: implications for the evolution of the ribokinase superfamily.
Functional analysis of the glycero-manno-heptose 7-phosphate kinase domain from the bifunctional HldE protein, which is involved in ADP-L-glycero-D-manno-heptose biosynthesis.
Structure of Methanocaldococcus jannaschii nucleoside kinase: an archaeal member of the ribokinase family.
Evidence for a catalytic Mg2+ ion and effect of phosphate on the activity of Escherichia coli phosphofructokinase-2: regulatory properties of a ribokinase family member.
Ribokinase from E. coli: expression, purification, and substrate specificity.
Crystal structure of pyridoxal kinase from the Escherichia coli pdxK gene: implications for the classification of pyridoxal kinases.
The crystal structure of an ADP complex of Bacillus subtilis pyridoxal kinase provides evidence for the parallel emergence of enzyme activity during evolution.
Althogh potassium ion and phosphate ion are included as cofactors, they are not likely to be involved in catalysis (see [9], [13], [24]). This enzyme is homologous to human counterpart enzyme (S00541 in EzCatDB).