M00175
type: Enzyme
rlcp: p1141
cath: Rossmann fold
cath: DNA polymerase; domain 1
cath: Nucleotidyltransferase; domain 5
cath: Taq DNA Polymerase; Chain T, domain 4
cath: Alpha-Beta Plaits
cath: http://ezcatdb.cbrc.jp/EzCatDB/cath/1.10.473.10
ec: https://purl.uniprot.org/enzyme/3.1.11.3
ec: https://purl.uniprot.org/enzyme/2.7.7.7
uniprot: P19821
uniprot: P52026
uniprot: Q04957
kegg enzyme: exodeoxyribonuclease (lambda-induced)
  type: KeggEnzyme
  ec: https://purl.uniprot.org/enzyme/3.1.11.3
kegg pathway: Purine metabolism
kegg pathway: Pyrimidine metabolism
kegg cofactor: Divalent metal
kegg substrate: Deoxynucleoside triphosphate
kegg substrate: DNA(n)
kegg substrate: H2O
kegg product: Pyrophosphate
kegg product: DNA(n)
kegg product: 5'-Phosphomononucleotides
pdb: 1bgxT01
pdb: 1cmwA01
pdb: 1taqA01
pdb: 1tauA01
pdb: 1bgxT02
pdb: 1cmwA02
pdb: 1taqA02
pdb: 1tauA02
pdb: 1bgxT03
pdb: 1cmwA03
pdb: 1taqA03
pdb: 1tauA03
pdb: 1jxeA01
pdb: 1ktqA01
pdb: 1qssA01
pdb: 1qsyA01
pdb: 1qtmA01
pdb: 2ktqA01
pdb: 3ktqA01
pdb: 4ktqA01
pdb: 5ktqA01
pdb: 1l3sA01
pdb: 1l3tA01
pdb: 1l3uA01
pdb: 1l3vA01
pdb: 1l5uA01
pdb: 1lv5A01
pdb: 1lv5B01
pdb: 1xwlA01
pdb: 2bdpA01
pdb: 3bdpA01
pdb: 4bdpA01
pdb: 1bgxT04
pdb: 1cmwA04
pdb: 1taqA04
pdb: 1tauA04
pdb: 1jxeA02
pdb: 1ktqA02
pdb: 1qssA02
pdb: 1qsyA02
pdb: 1qtmA02
pdb: 2ktqA02
pdb: 3ktqA02
pdb: 4ktqA02
pdb: 5ktqA02
pdb: 1l3sA02
pdb: 1l3tA02
pdb: 1l3uA02
pdb: 1l3vA02
pdb: 1l5uA02
pdb: 1lv5A02
pdb: 1lv5B02
pdb: 1xwlA02
pdb: 2bdpA02
pdb: 3bdpA02
pdb: 4bdpA02
pdb: 1bgxT05

Rossmann fold
type: Cath
references: http://www.cathdb.info/version/latest/superfamily/3.40.50.1010
catalytic domain: index.html

DNA polymerase; domain 1
type: Cath
references: http://www.cathdb.info/version/latest/superfamily/1.10.150.20

Nucleotidyltransferase; domain 5
type: Cath
references: http://www.cathdb.info/version/latest/superfamily/3.30.420.10

Taq DNA Polymerase; Chain T, domain 4
type: Cath
references: http://www.cathdb.info/version/latest/superfamily/1.20.1060.10

Alpha-Beta Plaits
type: Cath
references: http://www.cathdb.info/version/latest/superfamily/3.30.70.370
catalytic domain: index.html

Purine metabolism
type: KeggPathway
references: KEGG:MAP00230
ec: https://purl.uniprot.org/enzyme/2.7.7.7

Pyrimidine metabolism
type: KeggPathway
references: KEGG:MAP00240
ec: https://purl.uniprot.org/enzyme/2.7.7.7

Divalent metal
type: KeggCofactor
references: KEGG:C02148
ec: https://purl.uniprot.org/enzyme/3.1.11.3
ec: https://purl.uniprot.org/enzyme/2.7.7.7
compound type: divalent metal (Ca2+, Mg2+)

Deoxynucleoside triphosphate
type: KeggSubstrate
references: KEGG:C00677
ec: https://purl.uniprot.org/enzyme/2.7.7.7
compound type: nucleotide

DNA(n)
type: KeggSubstrate
references: KEGG:C00039
ec: https://purl.uniprot.org/enzyme/2.7.7.7
compound type: nucleic acids
label: DNA(n+1)
ec: https://purl.uniprot.org/enzyme/3.1.11.3
type: KeggProduct

H2O
type: KeggSubstrate
references: KEGG:C00001
ec: https://purl.uniprot.org/enzyme/3.1.11.3
compound type: H2O
references: CHEBI:15377
references: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi

Pyrophosphate
type: KeggProduct
references: KEGG:C00013
ec: https://purl.uniprot.org/enzyme/2.7.7.7
compound type: phosphate group/phosphate ion
references: CHEBI:29888
references: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi

5'-Phosphomononucleotides
type: KeggProduct
references: KEGG:C01150
ec: https://purl.uniprot.org/enzyme/3.1.11.3
compound type: nucleotide

1bgxT01
type: Pdb
references: 1bgx
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1bgx
cofactor binding residue: ASP 18;ASP 119(divalent metal-1);ASP 142(divalent metal-1 & -2);ASP 144(divalent metal-2);GLU 117;ASP 120(divalent metal-3)

1cmwA01
type: Pdb
references: 1cmw
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1cmw
cofactor binding residue: ASP 18;ASP 119(divalent metal-1);ASP 142(divalent metal-1 & -2);ASP 144(divalent metal-2);GLU 117;ASP 120(divalent metal-3)

1taqA01
type: Pdb
references: 1taq
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1taq
cofactor binding residue: ASP 18;ASP 119(divalent metal-1);ASP 142(divalent metal-1 & -2);ASP 144(divalent metal-2);GLU 117;ASP 120(divalent metal-3)

1tauA01
type: Pdb
references: 1tau
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1tau
cofactor binding residue: ASP 18;ASP 119(divalent metal-1);ASP 142(divalent metal-1 & -2);ASP 144(divalent metal-2);GLU 117;ASP 120(divalent metal-3)

1bgxT05
type: Pdb
references: 1bgx
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1bgx
catalytic residue: ARG 587
cofactor binding residue: ASP 610;TYR 611(divalent metal-2);ASP 785(divalent metal-1 & -2);GLU 786(divalent metal-1)
main chain in catalysis: GLN 613

1cmwA05
type: Pdb
references: 1cmw
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1cmw
catalytic residue: ARG 587
cofactor binding residue: ASP 610;TYR 611(divalent metal-2);ASP 785(divalent metal-1 & -2);GLU 786(divalent metal-1)
main chain in catalysis: GLN 613

1taqA05
type: Pdb
references: 1taq
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1taq
catalytic residue: ARG 587
cofactor binding residue: ASP 610;TYR 611(divalent metal-2);ASP 785(divalent metal-1 & -2);GLU 786(divalent metal-1)
main chain in catalysis: GLN 613
comment: mutant S575C, S576C, S577C

1tauA05
type: Pdb
references: 1tau
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1tau
catalytic residue: ARG 587
cofactor binding residue: ASP 610;TYR 611(divalent metal-2);ASP 785(divalent metal-1 & -2);GLU 786(divalent metal-1)
main chain in catalysis: GLN 613

1jxeA03
type: Pdb
references: 1jxe
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1jxe
catalytic residue: ARG 587
cofactor binding residue: ASP 610;TYR 611(divalent metal-2);ASP 785(divalent metal-1 & -2);GLU 786(divalent metal-1)
main chain in catalysis: GLN 613

1ktqA03
type: Pdb
references: 1ktq
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1ktq
catalytic residue: ARG 587
cofactor binding residue: ASP 610;TYR 611(divalent metal-2);ASP 785(divalent metal-1 & -2);GLU 786(divalent metal-1)
main chain in catalysis: GLN 613

1qssA03
type: Pdb
references: 1qss
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1qss
catalytic residue: ARG 587
cofactor binding residue: ASP 610;TYR 611(divalent metal-2);ASP 785(divalent metal-1 & -2);GLU 786(divalent metal-1)
main chain in catalysis: GLN 613

1qsyA03
type: Pdb
references: 1qsy
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1qsy
catalytic residue: ARG 587
cofactor binding residue: ASP 610;TYR 611(divalent metal-2);ASP 785(divalent metal-1 & -2);GLU 786(divalent metal-1)
main chain in catalysis: GLN 613

1qtmA03
type: Pdb
references: 1qtm
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1qtm
catalytic residue: ARG 587
cofactor binding residue: ASP 610;TYR 611(divalent metal-2);ASP 785(divalent metal-1 & -2);GLU 786(divalent metal-1)
main chain in catalysis: GLN 613

2ktqA03
type: Pdb
references: 2ktq
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:2ktq
catalytic residue: ARG 587
cofactor binding residue: ASP 610;TYR 611(divalent metal-2);ASP 785(divalent metal-1 & -2);GLU 786(divalent metal-1)
main chain in catalysis: GLN 613

3ktqA03
type: Pdb
references: 3ktq
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:3ktq
catalytic residue: ARG 587
cofactor binding residue: ASP 610;TYR 611(divalent metal-2);ASP 785(divalent metal-1 & -2);GLU 786(divalent metal-1)
main chain in catalysis: GLN 613

4ktqA03
type: Pdb
references: 4ktq
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:4ktq
catalytic residue: ARG 587
cofactor binding residue: ASP 610;TYR 611(divalent metal-2);ASP 785(divalent metal-1 & -2);GLU 786(divalent metal-1)
main chain in catalysis: GLN 613

5ktqA03
type: Pdb
references: 5ktq
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:5ktq
catalytic residue: ARG 587
cofactor binding residue: ASP 610;TYR 611(divalent metal-2);ASP 785(divalent metal-1 & -2);GLU 786(divalent metal-1)
main chain in catalysis: GLN 613

1l3sA03
type: Pdb
references: 1l3s
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1l3s
catalytic residue: ARG 629
cofactor binding residue: ASP 653;TYR 654(divalent metal-2);ASP 830(divalent metal-1 & -2);GLU 831(divalent metal-1)
main chain in catalysis: GLN 656

1l3tA03
type: Pdb
references: 1l3t
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1l3t
catalytic residue: ARG 629
cofactor binding residue: ASP 653;TYR 654(divalent metal-2);ASP 830(divalent metal-1 & -2);GLU 831(divalent metal-1)
main chain in catalysis: GLN 656

1l3uA03
type: Pdb
references: 1l3u
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1l3u
catalytic residue: ARG 629
cofactor binding residue: ASP 653;TYR 654(divalent metal-2);ASP 830(divalent metal-1 & -2);GLU 831(divalent metal-1)
main chain in catalysis: GLN 656

1l3vA03
type: Pdb
references: 1l3v
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1l3v
catalytic residue: ARG 629
cofactor binding residue: ASP 653;TYR 654(divalent metal-2);ASP 830(divalent metal-1 & -2);GLU 831(divalent metal-1)
main chain in catalysis: GLN 656

1l5uA03
type: Pdb
references: 1l5u
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1l5u
catalytic residue: ARG 629
cofactor binding residue: ASP 653;TYR 654(divalent metal-2);ASP 830(divalent metal-1 & -2);GLU 831(divalent metal-1)
main chain in catalysis: GLN 656

1lv5A03
type: Pdb
references: 1lv5
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1lv5
catalytic residue: ARG 629
cofactor binding residue: ASP 653;TYR 654(divalent metal-2);ASP 830(divalent metal-1 & -2);GLU 831(divalent metal-1)
main chain in catalysis: GLN 656

1lv5B03
type: Pdb
references: 1lv5
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1lv5
catalytic residue: ARG 629
cofactor binding residue: ASP 653;TYR 654(divalent metal-2);ASP 830(divalent metal-1 & -2);GLU 831(divalent metal-1)
main chain in catalysis: GLN 656

1xwlA03
type: Pdb
references: 1xwl
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1xwl
catalytic residue: ARG 629
cofactor binding residue: ASP 653;TYR 654(divalent metal-2);ASP 830(divalent metal-1 & -2);GLU 831(divalent metal-1)
main chain in catalysis: GLN 656

2bdpA03
type: Pdb
references: 2bdp
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:2bdp
catalytic residue: ARG 629
cofactor binding residue: ASP 653;TYR 654(divalent metal-2);ASP 830(divalent metal-1 & -2);GLU 831(divalent metal-1)
main chain in catalysis: GLN 656

3bdpA03
type: Pdb
references: 3bdp
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:3bdp
catalytic residue: ARG 629
cofactor binding residue: ASP 653;TYR 654(divalent metal-2);ASP 830(divalent metal-1 & -2);GLU 831(divalent metal-1)
main chain in catalysis: GLN 656

4bdpA03
type: Pdb
references: 4bdp
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:4bdp
catalytic residue: ARG 629
cofactor binding residue: ASP 653;TYR 654(divalent metal-2);ASP 830(divalent metal-1 & -2);GLU 831(divalent metal-1)
main chain in catalysis: GLN 656

1bgxT06
type: Pdb
references: 1bgx
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1bgx
catalytic residue: HIS 639;ARG 659;LYS 663
main chain in catalysis: ILE 614

1cmwA06
type: Pdb
references: 1cmw
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1cmw
catalytic residue: HIS 639;ARG 659;LYS 663
main chain in catalysis: ILE 614

1taqA06
type: Pdb
references: 1taq
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1taq
catalytic residue: HIS 639;ARG 659;LYS 663
main chain in catalysis: ILE 614

1tauA06
type: Pdb
references: 1tau
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1tau
catalytic residue: HIS 639;ARG 659;LYS 663
main chain in catalysis: ILE 614

1jxeA04
type: Pdb
references: 1jxe
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1jxe
catalytic residue: HIS 639;ARG 659;LYS 663
main chain in catalysis: ILE 614

1ktqA04
type: Pdb
references: 1ktq
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1ktq
catalytic residue: HIS 639;ARG 659;LYS 663
main chain in catalysis: ILE 614

1qssA04
type: Pdb
references: 1qss
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1qss
catalytic residue: HIS 639;ARG 659;LYS 663
main chain in catalysis: ILE 614

1qsyA04
type: Pdb
references: 1qsy
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1qsy
catalytic residue: HIS 639;ARG 659;LYS 663
main chain in catalysis: ILE 614

1qtmA04
type: Pdb
references: 1qtm
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1qtm
catalytic residue: HIS 639;ARG 659;LYS 663
main chain in catalysis: ILE 614

2ktqA04
type: Pdb
references: 2ktq
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:2ktq
catalytic residue: HIS 639;ARG 659;LYS 663
main chain in catalysis: ILE 614

3ktqA04
type: Pdb
references: 3ktq
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:3ktq
catalytic residue: HIS 639;ARG 659;LYS 663
main chain in catalysis: ILE 614

4ktqA04
type: Pdb
references: 4ktq
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:4ktq
catalytic residue: HIS 639;ARG 659;LYS 663
main chain in catalysis: ILE 614

5ktqA04
type: Pdb
references: 5ktq
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:5ktq
catalytic residue: HIS 639;ARG 659;LYS 663
main chain in catalysis: ILE 614

1l3sA04
type: Pdb
references: 1l3s
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1l3s
catalytic residue: HIS 682;ARG 702;LYS 706
main chain in catalysis: ILE 657

1l3tA04
type: Pdb
references: 1l3t
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1l3t
catalytic residue: HIS 682;ARG 702;LYS 706
main chain in catalysis: ILE 657

1l3uA04
type: Pdb
references: 1l3u
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1l3u
catalytic residue: HIS 682;ARG 702;LYS 706
main chain in catalysis: ILE 657

1l3vA04
type: Pdb
references: 1l3v
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1l3v
catalytic residue: HIS 682;ARG 702;LYS 706
main chain in catalysis: ILE 657

1l5uA04
type: Pdb
references: 1l5u
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1l5u
catalytic residue: HIS 682;ARG 702;LYS 706
main chain in catalysis: ILE 657

1lv5A04
type: Pdb
references: 1lv5
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1lv5
catalytic residue: HIS 682;ARG 702;LYS 706
main chain in catalysis: ILE 657

1lv5B04
type: Pdb
references: 1lv5
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1lv5
catalytic residue: HIS 682;ARG 702;LYS 706
main chain in catalysis: ILE 657

1xwlA04
type: Pdb
references: 1xwl
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:1xwl
catalytic residue: HIS 682;ARG 702;LYS 706
main chain in catalysis: ILE 657

2bdpA04
type: Pdb
references: 2bdp
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:2bdp
catalytic residue: HIS 682;ARG 702;LYS 706
main chain in catalysis: ILE 657

3bdpA04
type: Pdb
references: 3bdp
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:3bdp
catalytic residue: HIS 682;ARG 702;LYS 706
main chain in catalysis: ILE 657

4bdpA04
type: Pdb
references: 4bdp
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
references: PDB:4bdp
catalytic residue: HIS 682;ARG 702;LYS 706
main chain in catalysis: ILE 657

Analogue
compound: Deoxynucleoside triphosphate
pdb: 1qssA03
ligand het code: DG3

Analogue
compound: Deoxynucleoside triphosphate
pdb: 1qsyA03
ligand het code: DAD

Analogue
compound: Deoxynucleoside triphosphate
pdb: 2ktqA03
ligand het code: DCT

Analogue
compound: Deoxynucleoside triphosphate
pdb: 3ktqA03
ligand het code: DCT

Analogue
compound: DNA(n)
pdb: 1qssA03
ligand het code: G-A-C-C-A-C-G-G-C-G-C-DDG (chain B)

Analogue
compound: DNA(n)
pdb: 1qsyA03
ligand het code: G-A-C-C-A-C-G-G-C-G-C-2DA (chain B)

Analogue
compound: DNA(n)
pdb: 1qtmA03
ligand het code: G-A-C-C-A-C-G-G-C-G-C-2DT (chain B)

Analogue
compound: DNA(n)
pdb: 2ktqA03
ligand het code: G-A-C-C-A-C-G-G-C-G-C-DOC (chain B)

Analogue
compound: DNA(n)
pdb: 3ktqA03
ligand het code: G-A-C-C-A-C-G-G-C-G-C-DOC (chain B)

Analogue
compound: DNA(n)
pdb: 4ktqA03
ligand het code: G-A-C-C-A-C-G-G-C-G-C-DOC (chain B)

Analogue
compound: DNA(n)
pdb: 1lv5A03
ligand het code: G-G-A-T-C-A-G-C-G-A (chain C)

Analogue
compound: DNA(n)
pdb: 1lv5B03
ligand het code: G-G-A-T-C-A-G-C-G-A (chain E)

Analogue
compound: DNA(n)
pdb: 3bdpA03
ligand het code: G-C-A-T-G-A-T-G-C-2DT (chain P)

Analogue
compound: Pyrophosphate
pdb: 1l3sA04
ligand het code: SO4_910

Analogue
compound: Pyrophosphate
pdb: 1l3tA04
ligand het code: SO4_910

Analogue
compound: Pyrophosphate
pdb: 1l3uA04
ligand het code: SO4_910

Analogue
compound: Pyrophosphate
pdb: 1l3vA04
ligand het code: SO4_910

Analogue
compound: Pyrophosphate
pdb: 1l5uA04
ligand het code: SO4_910

Analogue
compound: Pyrophosphate
pdb: 2bdpA04
ligand het code: SO4_910

Analogue
compound: Pyrophosphate
pdb: 3bdpA04
ligand het code: SO4_910

Analogue
compound: Pyrophosphate
pdb: 4bdpA04
ligand het code: SO4_910

ReferenceForCatalyticMechanism
reference index: 5

ReferenceForCatalyticMechanism
reference index: 6
reference section: Fig.10, p.30-31
reference step: 2

ReferenceForCatalyticMechanism
reference index: 8

ReferenceForCatalyticMechanism
reference index: 12
reference section: Fig.4, Fig.5, p.34-36

ReferenceForCatalyticMechanism
reference index: 13
reference section: Fig.3

ReferenceForCatalyticMechanism
reference index: 14
reference section: p.2026

ReferenceForCatalyticMechanism
reference index: 16
reference section: p.615-616

ReferenceForCatalyticMechanism
reference index: 20

ReferenceForCatalyticMechanism
reference index: 22
reference section: p.101-102

ReferenceForCatalyticMechanism
reference index: 23
reference section: p.7521

ReferenceForCatalyticMechanism
reference index: 26
reference section: p.372

ReferenceForCatalyticMechanism
reference index: 28
reference section: p.306

ReferenceForCatalyticMechanism
reference index: 30
reference section: Fig.3

ReferenceForCatalyticMechanism
reference index: 32
reference section: Fig.1

ReferenceForCatalyticMechanism
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reference section: Fig.1

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DNA polymerase I of Mycobacterium tuberculosis: functional role of a conserved aspartate in the hinge joining the M and N helices.
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  item: Modak MJ

Mutant Thermotoga neapolitana DNA polymerase I: altered catalytic properties for non-templated nucleotide addition and incorporation of correct nucleotides.
type: BibliographicResource
references: http://www.ncbi.nlm.nih.gov/pubmed/12364611
journal: Nucleic Acids Res
volume: 30
pages: 4314-20
published year: 2002
authors:
  item: Yang SW
  item: Astatke M
  item: Potter J
  item: Chatterjee DK

Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations.
type: BibliographicResource
references: http://www.ncbi.nlm.nih.gov/pubmed/12649320
journal: Proc Natl Acad Sci U S A
volume: 100
pages: 3895-900
published year: 2003
authors:
  item: Johnson SJ
  item: Taylor JS
  item: Beese LS
references: http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl

lambda exonuclease
type: KeggEnzyme
ec: https://purl.uniprot.org/enzyme/3.1.11.3

phage lambda-induced exonuclease
type: KeggEnzyme
ec: https://purl.uniprot.org/enzyme/3.1.11.3

Escherichia coli exonuclease IV
type: KeggEnzyme
ec: https://purl.uniprot.org/enzyme/3.1.11.3

E. coli exonuclease IV
type: KeggEnzyme
ec: https://purl.uniprot.org/enzyme/3.1.11.3

exodeoxyribonuclease IV
type: KeggEnzyme
ec: https://purl.uniprot.org/enzyme/3.1.11.3

exonuclease IV
type: KeggEnzyme
ec: https://purl.uniprot.org/enzyme/3.1.11.3

DNA-directed DNA polymerase
type: KeggEnzyme
ec: https://purl.uniprot.org/enzyme/2.7.7.7

DNA polymerase I
type: KeggEnzyme
ec: https://purl.uniprot.org/enzyme/2.7.7.7

DNA polymerase II
type: KeggEnzyme
ec: https://purl.uniprot.org/enzyme/2.7.7.7

DNA polymerase III
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ec: https://purl.uniprot.org/enzyme/2.7.7.7

DNA polymerase alpha
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ec: https://purl.uniprot.org/enzyme/2.7.7.7

DNA polymerase beta
type: KeggEnzyme
ec: https://purl.uniprot.org/enzyme/2.7.7.7

DNA polymerase gamma
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DNA nucleotidyltransferase (DNA-directed)
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DNA nucleotidyltransferase (DNA-directed)
type: KeggEnzyme
ec: https://purl.uniprot.org/enzyme/2.7.7.7

deoxyribonucleate nucleotidyltransferase
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ec: https://purl.uniprot.org/enzyme/2.7.7.7

deoxynucleate polymerase
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ec: https://purl.uniprot.org/enzyme/2.7.7.7

deoxyribonucleic acid duplicase
type: KeggEnzyme
ec: https://purl.uniprot.org/enzyme/2.7.7.7

deoxyribonucleic acid polymerase
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deoxyribonucleic duplicase
type: KeggEnzyme
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deoxyribonucleic polymerase
type: KeggEnzyme
ec: https://purl.uniprot.org/enzyme/2.7.7.7

deoxyribonucleic polymerase I
type: KeggEnzyme
ec: https://purl.uniprot.org/enzyme/2.7.7.7

DNA duplicase
type: KeggEnzyme
ec: https://purl.uniprot.org/enzyme/2.7.7.7

DNA nucleotidyltransferase
type: KeggEnzyme
ec: https://purl.uniprot.org/enzyme/2.7.7.7

DNA polymerase
type: KeggEnzyme
ec: https://purl.uniprot.org/enzyme/2.7.7.7

DNA replicase
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DNA-dependent DNA polymerase
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duplicase
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Klenow fragment
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sequenase
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Taq DNA polymerase
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Taq Pol I
type: KeggEnzyme
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Tca DNA polymerase
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ec: https://purl.uniprot.org/enzyme/2.7.7.7