Inhibition of cathepsin G by 4H-3,1-benzoxazin-4-ones.
Neutrophil elastase and cathepsin G: structure, function, and biological control.
Nonchromogenic hydrolysis of elastase and cathepsin G p-nitroanilide substrates by Pseudomonas aeruginosa elastase.
Ionic inhibitors of human leukocyte elastase: pyridinium and phenyl carboxylate derivatives of 3-alkyl-N-hydroxysuccinimide.
Irreversible inhibition of serine proteases by peptide derivatives of (alpha-aminoalkyl)phosphonate diphenyl esters.
Insight into the nature and site of oxygen-centered free radical generation by endothelial cell monolayers using a novel spin trapping technique.
Defibrotide inhibits platelet activation by cathepsin G released from stimulated polymorphonuclear leukocytes.
The isoforms of human neutrophil elastase and cathepsin G differ in their carbohydrate side chain structures.
Cathepsin G inactivates human protein S in vitro.
Mechanism-based inhibition of human leukocyte elastase and cathepsin G by substituted dihydrouracils.
Interleukin-8 processing by neutrophil elastase, cathepsin G and proteinase-3.
The Gabriel-Colman rearrangement in biological systems: design, synthesis and biological evaluation of phthalimide and saccharin derivatives as potential mechanism-based inhibitors of human leukocyte elastase, cathepsin G and proteinase 3.
Isoxazoline derivatives as potential inhibitors of the proteolytic enzymes human leukocyte elastase, cathepsin G and proteinase 3: a structure-activity relationship study.
Design, synthesis, and in vitro inhibitory activity toward human leukocyte elastase, cathepsin G, and proteinase 3 of saccharin-derived sulfones and congeners.
The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities.
Structure-based design of a general class of mechanism-based inhibitors of the serine proteinases employing a novel amino acid-derived heterocyclic scaffold.
Inhibition of human immunodeficiency virus type 1 infectivity by secretory leukocyte protease inhibitor occurs prior to viral reverse transcription.
Proteolysis of factor V by cathepsin G and elastase indicates that cleavage at Arg1545 optimizes cofactor function by facilitating factor Xa binding.
Angiotensin II generation at the cell surface of activated neutrophils: novel cathepsin G-mediated catalytic activity that is resistant to inhibition.
New, sensitive fluorogenic substrates for human cathepsin G based on the sequence of serpin-reactive site loops.
Enzymatic and molecular biochemical characterizations of human neutrophil elastases and a cathepsin G-like enzyme.
NMR solution structure of Apis mellifera chymotrypsin/cathepsin G inhibitor-1 (AMCI-1): structural similarity with Ascaris protease inhibitors.
Characterization of the necrotic cleavage of poly(ADP-ribose) polymerase (PARP-1): implication of lysosomal proteases.
Nonpeptide inhibitors of cathepsin G: optimization of a novel beta-ketophosphonic acid lead by structure-based drug design.
This enzyme belongs to the peptidase family-S1. According to the literature [14], this enzyme has got a similar catalytic triad (Ser/His/Asp) and an oxyanion hole, to that of trypsin, suggesting a similar mechanism.