dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate,quinone)
NAD(P)H: (quinone-acceptor)oxidoreductase
viologen accepting pyridine nucleotide oxidoreductase
reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase
NAD(P)H:(quinone-acceptor) oxidoreductase
Molecular basis of the catalytic differences among DT-diaphorase of human, rat, and mouse.
Bioreductive activation of mitomycin C by DT-diaphorase.
Antioxidant and prooxidant functions of DT-diaphorase in quinone metabolism.
The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprotection and chemotherapy: mechanism of the two-electron reduction.
Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT-diaphorase).
Structure and mechanism of cytosolic quinone reductases.
Crystal structure of human quinone reductase type 2, a metalloflavoprotein.
Crystal structure of human DT-diaphorase: a model for interaction with the cytotoxic prodrug 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954).
Molecular characterization of binding of substrates and inhibitors to DT-diaphorase: combined approach involving site-directed mutagenesis, inhibitor-binding analysis, and computer modeling.
Structure-function studies of DT-diaphorase (NQO1) and NRH: quinone oxidoreductase (NQO2).
Mechanisms of action of quinone-containing alkylating agents. I: NQO1-directed drug development.
Structures of recombinant human and mouse NAD(P)H:quinone oxidoreductases: species comparison and structural changes with substrate binding and release.
Flavoenzymes: diverse catalysts with recurrent features.
Structures of mammalian cytosolic quinone reductases.
Structure-based development of anticancer drugs: complexes of NAD(P)H:quinone oxidoreductase 1 with chemotherapeutic quinones.
Characterization of a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1 by biochemical, X-ray crystallographic, and mass spectrometric approaches.
Mechanism of NAD(P)H:quinone reductase: Ab initio studies of reduced flavin.
Two-electron reduction of quinones by rat liver NAD(P)H:quinone oxidoreductase: quantitative structure-activity relationships.
Kinetic mechanism of quinone oxidoreductase 2 and its inhibition by the antimalarial quinolines.